apache

<IfModule mod_rewrite.c>
RewriteEngine On
#Block domain
RewriteCond %{HTTP_REFERER} www.abc.com [NC]
RewriteRule ^(.*)$ -[F]
</IfModule>

iis7及以上版本

<?xml version="1.0" encoding="UTF-8"?>
<configuration>
    <system.webServer>
     <rewrite>  
       <rules>
         <rule name="屏蔽访问">
             <match url="^(.*)$" ignoreCase="false" />
             <conditions logicalGrouping="MatchAll">
                 <add input="{HTTP_REFERER}" pattern="www.abc.com"  ignoreCase="true" />
             </conditions>
             <action type="AbortRequest" />
          </rule>  
        </rules>  
      </rewrite>  
     </system.webServer>
</configuration>

nginx

if ($http_referer !~* "www.abc.com|^$") {
    return 444;
}